Thomas Eklund, member of the board, has announced that he resigns effective today from the Board of SciBase Holding AB at his own request.
Thomas has decided to resign from SciBase and other Board positions due to lack of time.
"Thomas' valuable contributions and insights during his time at SciBase have been highly appreciated by both the Board of Directors and the management. I want to take the opportunity to thank Thomas for all the time he has spent and his contributions to make SciBase a successful Company. Unfortunately, time is a scarce resource and I wish him all the best in his future endeavors," says Tord Lendau, chairman of the Board, SciBase Holding AB.
The Board of Directors retains a quorum despite Thomas Eklund leaving. The Nomination Committee has not yet drafted a proposal for resolution at the 2020 AGM, concerning Members of the Board.
Stockholm, November 13, 2019
SciBase Holding AB (publ)
For more information, please contact: Tord Lendau, Chairman of the board, phone +46 (0)70 810 01 67
About SciBase and Nevisense SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. Further development has led to Nevisense also being used as a tool to assess the skin barrier and inflammation. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and an FDA approval (PMA) in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on First North Growth Market ("SCIB"). Further information is available at www.scibase.com.
SciBase, a leading manufacturer of solutions within skin diagnostics announced today that they will present at the Swiss-Nordic Bio 2020 conference in Zurich this week.
"I look forward to presenting an update on our progress at SciBase in Zurich. On the back of the release of Nevisense 3.0 in 2018 we have seen a significant increase in 2019 in both usage and sales of our Nevisense system for the detection of melanoma. At the same time we've been pleased to see increased traction for Nevisense in the US and look forward to discussing our plans for that market.
I will also present an update on the new clinical applications we plan to launch during 2020, and our upcoming product Nevisense Go.
We are seeing significant interest from both the research world and from industry in our new skin barrier assessment application, where our goal is to improve management of chronic and prevalent atopic diseases such as atopic dermatitis. This application has been developed through our cooperation with SIAF (Swiss Institute for Allergy and Asthma research). With SIAF being based in Switzerland, we see it as a good opportunity to present SciBase and our products and applications to potential investors and partners. We are also pleased that Professor Cezmi Akdis, Director of SIAF, will also attend the conference." Simon Grant, CEO of SciBase.
For more information please contact: Simon Grant, CEO SciBase
Tel: +46 72 887 43 99
Email: [email protected]
About SciBase and Nevisense SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. Further development has led to Nevisense also being used as a tool to assess the skin barrier and inflammation. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and an FDA approval (PMA) in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on First North Growth Market ("SCIB"). Further information is available at www.scibase.com.
SciBase today announces the first multi system order from a large dermatology practice group. Advanced Dermatology, P.C. is a group of over 40 dermatology practices in the New York tri-state area.
The initial order consists of six Nevisense systems and electrodes. Advanced Dermatology, P.C. with a total of over 40 dermatology clinics is one of the largest practice groups in the New York tri-state area; and has the potential to become a key customer for SciBase.
"We are looking forward to integrating Nevisense into our practice group and providing our patients with innovative FDA approved technology for the earliest detection possible of melanoma" said Dr. Fox, founder and director of Advanced Dermatology, P.C., the Center for Laser and Cosmetic Surgery.
"Part of our US strategy focuses on large groups of dermatology practices. This is the first multiple site order we receive from such a group. They have tested Nevisense in a pilot and have now placed an initial order for six Nevisense systems and electrodes. Though a relatively moderate order size, this is an important recognition of the potential of Nevisense as we work to penetrate the large US market", says Simon Grant, CEO of SciBase.
For more information, please contact: Simon Grant, CEO SciBase
Tel: +46 72 887 43 99
Email: [email protected]
SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. Further development has led to Nevisense also being used as a tool to assess the skin barrier and inflammation. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and an FDA approval (PMA) in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on First North Growth Market ("SCIB"). Further information is available at www.scibase.com.
Frederick Johansson (representing SEB Venture Capital,
Filip Petersson (SEB pensionsstiftelse),
Christer Jönsson (Fouriertransform),
Tord Lendau (Chairman of the Board).
The appointments have been made in accordance with the instructions regarding principles for the appointment of the company nominating committee which were determined at the Annual General Meeting of SciBase Holding on May 16, 2019.
The Annual General Meeting of SciBase Holding AB (publ) will be held on May 14, 2020 in Stockholm.
Shareholders who wish to have an item considered at the Annual General Meeting can submit a request to the Board to this effect. Such a request for an item to be considered is to be sent to SciBase Holding AB (publ), Att: Chairman of the Board, Box 3337, 103 67 Stockholm, and must have been received by the Board no later than seven weeks before the Annual General Meeting, or otherwise in such good time that the matter, where necessary, can be included in the notice to attend the Annual General Meeting.
Stockholm, November 8, 2019
SciBase Holding AB (publ)
For more information, please contact: Tord Lendau, Chairmain of the board, phone +46 (0)70 810 01 67
About SciBase and Nevisense SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. Further development has led to Nevisense also being used as a tool to assess the skin barrier and inflammation. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and an FDA approval (PMA) in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on First North Growth Market ("SCIB"). Further information is available at www.scibase.com..
STOCKHOLM, Sweden, - November 12, 2019 - SciBase a leading developer of electrical impedance spectroscopy systems in dermatology, announced today that The Kimberly and Eric J. Waldman Department of Dermatology at Mount Sinai has become the first Health System in the United States to order multiple Nevisense systems in their new melanoma center. The Mount Sinai health system encompasses eight hospitals, a leading medical school, and a vast network of ambulatory practices throughout the greater New York region making it the largest system in the region.
"We are excited about integrating the Nevisense system in our new melanoma center and offer our patients advanced technology to optimize the clinical management of their atypical lesions. It further supports our commitment to adopt next-generation solutions to improve patient care and outcomes while offering our providers state-of-the-art tools to do so" said Dr. Mark Lebwohl, Waldman Professor and Chairman of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai.
"The inclusion of EIS technology will allow us to provide patients with important risk information. This will help differentiate the Mount Sinai melanoma center while also providing our patients with best in class care", said Dr. Jonathan Ungar, assistant professor of dermatology and medical education at Mount Sinai.
"We are observing a demand for augmented intelligence within dermatology in the US and SciBase is proud to install multiple Nevisense systems within one of the largest health systems in the US and the largest in the New York region." said Simon Grant, Chief Executive Officer of Scibase. "This multi system order marks a key milestone in SciBase' US market penetration strategy and we are excited about the growing adoption of the Nevisense method."
For more information, please contact: Simon Grant, CEO SciBase
Tel: +46 72 887 43 99
Email: [email protected]
SciBase AB is a Swedish medical technology company and a global leader in breakthrough point-of-care technology for the evaluation of skin disorders such as skin cancer and atopic dermatitis. Their flagship product Nevisense assists physicians in the detection of melanoma at its earliest, most curable stage. Melanoma is the deadliest form of skin cancer and has an almost 100% cure rate if caught early. Further development has led to Nevisense also being used as a tool to assess the skin barrier and inflammation in research. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and is FDA Approved in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on First North Growth Market ("SCIB"). Further information is available at www.scibase.com.
At the annual general meeting of SciBase Holding AB (publ) on 16 May 2019 in Stockholm the shareholders adopted the below resolutions.
Resolution regarding adoption of the income statement and balance sheet and the consolidated income statement and consolidated balance sheet as well as resolutions in respect of allocation of the company's result according to the adopted balance sheet and discharge from liability
The meeting resolved to adopt the income statement and balance sheet and the consolidated income statement and consolidated balance sheet included in the annual report.
The meeting resolved to allocate the profit for the year in accordance with the board of directors’ proposal, i.e. SEK 135,443,035 was carried forward.
The meeting resolved to discharge the board members and managing director from liability for their management of the company's affairs during the preceding financial year.
Resolution regarding the remuneration for the board of directors and the auditor
The meeting resolved that remuneration for the Board of Directors and the auditor should be paid in accordance with the following:
A fee of SEK 200,000 shall be paid to the Chairman of the Board of Directors and SEK 150,000 to external members of the Board of Directors who are not employed by a larger shareholder in the Company.
Fees to the Company's auditor shall be paid in accordance with approved invoices.
Resolution on guidelines for determination of salary and other remuneration to senior management
The meeting resolved to adopt guidelines for determination of salary and other remuneration to senior management in accordance the board’s proposal.
Resolution regarding members of the board of directors and auditor
For the time until the end of the next annual general meeting, the meeting resolved to elect Tord Lendau (re-election), Thomas Eklund (re-election), Diana Ferro (re-election) and Thomas Taapken (re-election) as ordinary members of the board of directors.
PricewaterhouseCoopers AB (PwC) (re-election) was elected as auditor with Magnus Lagerberg as responsible auditor for the time until the end of the next annual general meeting.
Resolution regarding appointment of nominating committee
The meeting resolved to adopt principles for the appointment the nominating committee for the annual general meeting 2020 in accordance with the nominating committee’s proposal.
Resolution regarding authorization of the board of directors to issue new shares, issuance of warrants and/or convertibles
The meeting resolved to authorize the board of directors to, during the time until the next annual general meeting, on one or more occasions, decide upon issuances of new shares, issuance of warrants and/or convertibles. New issues of shares and issues of warrants and/or convertibles may occur with or without preferential rights for shareholders of the Company and may be made either in cash and/or by way of set-off or contribution in kind or otherwise on specific terms. The number of shares issued, or number of shares created in connection with exercise of warrants or conversion of convertibles, shall not exceed 1,661,810.
The information herein is such that shall be announced in accordance with the rules applied by Nasdaq First North. The information was submitted for publication at 7:00 pm on May 16, 2019.
About Skin Cancer
Skin cancer is one of the most common cancers in the world, accounting for nearly half of all cancers. It has been estimated that nearly half of all Americans who live to age 65 will develop skin cancer at least once. Malignant melanoma is the most fatal form of skin cancer causing the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 230,000 new cases of melanoma yearly.
About SciBase and Nevisense
SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and a US FDA-approval (PMA). Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on Nasdaq First North (“SCIB”). Further information is available at www.scibase.com.
The loss after tax amounted to TSEK 10,613 (10,298).
The loss per share amounted to SEK 0.64 (0.62).
The cash flow from current operations was negative in the amount of TSEK 9,900 (10,119).
The gross margin reached 53.3% (58.2%).
Electrode sales volume increased by 33% and reached 5,712 (4,304) units. Repeat sales of electrodes to existing customers increased by 41%.
The first half-year in figures
Net sales amounted to TSEK 4,536 (3,510).
The loss after tax amounted to TSEK 19,520 (19,955).
The loss per share amounted to SEK 1,17 (1.20).
The cash flow from current operations was negative in the amount of TSEK 18,850 (19,801).
The gross margin increased to 52.9% (51.7%).
Electrode sales volume increased by 38% and reached 11,792 (8,438) units. Repeat sales of electrodes to existing customers increased by 50%.
Important events during the quarter
Sales in the company’s key market Germany increased by 40% in the quarter following a further improvement in electrode sales.
An application for the Nevisense 3.0 software was submitted to the US FDA.
A new study was published that opened up the skin barrier assessment application for SciBase’s product Nevisense. The paper, entitled ‘Direct assessment of skin epithelial barrier by electrical impedance spectroscopy’, was published in the journal Allergy, European Journal of Allergy and Clinical Immunology.
Three scientific presentations described the use of EIS for skin barrier assessment at the EAACI (European Academy of Allergy and Clinical Immunology) meeting in June. SciBase presented the skin barrier application for the first time at an allergy conference.
Nevisense was included in the first US and European investigator-initiated studies utilizing Nevisense for skin barrier assessment.
The AGM 2019 was held on May 16th.
Important events after the end of the period
New Nevisense software was released in the EU that included wireless integration with the Heine digital dermoscopy system, skin barrier analysis tools and further ease-of-use improvements.
July 1 2018 -
Apr 1 - June 30
Jan 1 - June 30
June 30 2019
Jan 1 - Dec 31
THE GROUP
2019
2018
2019
2018
Rolling-12
2018
Net sales, SEK ths
2 168
1 571
4 536
3 510
7 925
6 899
Gross margin, %
53,3%
58,2%
52,9%
51,7%
52,7%
52,0%
Equity/Asset ratio, %
74,5%
92,0%
74,5%
92,0%
85,0%
88,1%
Net indebtness, multiple
0,34
0,09
0,34
0,09
0,18
0,13
Cash equivalents, SEK ths
46 772
85 231
46 772
85 231
46 772
67 514
Cashflow from operating activities, SEK ths
-9 900
-10 119
-18 850
-19 801
-36 532
-37 482
Earnings per share (before and after dilution), SEK
-0,64
-0,62
-1,17
-1,20
-2,63
-2,66
Shareholder's equity per share, SEK
3,10
5,76
3,10
5,76
6,96
4,30
Average number of shares, 000'
16 618
16 618
16 618
16 618
10 576
16 618
Number of shares at closing of period, 000'
16 618
16 618
16 618
16 618
16 618
16 618
Share price at end of period, SEK
4,34
6,45
4,34
6,45
4,34
3,10
Number of sold electrodes, pieces
5 712
4 304
11 792
8 438
15 920
12 566
Average number of employees
18
20
18
20
19
19
This interim report has not been subject to review by the Company’s auditors.
This information is information that SciBase Holding AB is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact person set out below, at 08.00 CET on August 22, 2019.
Contact person: Michael Colérus, CFO. +46 70 341 34 72
For more information, please contact: Simon Grant, CEO SciBase Phone: +46 72 887 43 99 Email: [email protected]
SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and a US FDA-approval (PMA). Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on Nasdaq First North (“SCIB”). Further information is available at www.scibase.com.
SciBase today announces the first sale and shipment of SciBase products for the evaluation of skin barrier function. The first shipment is to a prestigious hospital in Japan for research into skin barrier function in infants.
The skin’s barrier fulfils a very important role as it prevents external threats such as irritants, allergens and infectious agents from entering the body and prevents water from leaving the body. When these layers are defective or damaged, barrier related diseases can occur. The most common of these is atopic dermatitis (AD) or eczema. It has been shown, for example, that children with a defective or ‘leaky’ barrier are far more likely to develop eczema and then in turn are more likely to develop food allergies, allergic rhinosinusitis and asthma. Clinicians call this progression of disorders the ‘atopic’ or ‘allergic march’ and recent studies show this to be very-much barrier-related.
The challenge for Clinicians is that current methods are unreliable and cannot be used to assess skin barrier function in a routine clinical setting. This is where SciBase’s technology Electrical Impedance Spectroscopy (EIS) comes in. Nevisense can apply EIS in a clinical setting and this has the potential to provide clinicians with a quick and accurate assessment of the status of the skin barrier and better manage their patients.
“The publication of the first article in Allergy marked a milestone for SciBase, and we now have a second milestone with the first sale of equipment for use in assessing skin barrier function. The interest that we have seen, particularly from researchers, has been very encouraging. The potential applications are many and the market potential is large – much larger than for melanoma. We believe that this new application to evaluate skin barrier function could really be a breakthrough for SciBase as a Company and expect more sales to follow.”, says Simon Grant, CEO of SciBase.
The full article can be found here: https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13824
For more information, please contact:
Simon Grant, CEO SciBase Tel: +46 72 887 43 99 Email: [email protected]
SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. Further development has led to Nevisense also being used as a tool to assess the skin barrier and inflammation. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and a FDA clearance in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on First North Growth Market (“SCIB”). Further information is available at www.scibase.com.
At SciBase we have been very focused on two key development projects and a market launch over the last months, which explains the lack of CEO letters - my apologies! Now that we have come some way on the projects, I thought I’d take the chance to describe what has happened so far, and what we see coming in the near future.
The updated measurement method, Nevisense 3.0
Much of 2018 was spent overhauling the Nevisense measurement method for melanoma. Though we knew our method worked, we also knew that customers felt it involved too many steps and the time it took was too variable. Both these factors made it more difficult to include as a standard test in a busy dermatology clinic, where a single consultation often takes only 15 minutes.
Nevisense used a two-step measurement process – first a reference measurement on healthy skin and then a lesion measurement itself, and our goal was to remove the need for the reference measurement completely. The team worked extremely hard and found a way to extract reference information from the lesion measurement itself. When we validated the updated method in June last year, we saw that in addition to being simpler, the new process actually improved the clinical results.
We launched the new method in September, and I can say that within three months the majority of users had upgraded to the new method and are very happy with the improvements. With over ten thousand patients now tested with the new method, we see increased usage and significantly increased electrode sales – and to us this shows that the improvement was well worth the effort. The new clinical guidelines released in November were a bonus for us and are helping to cement Nevisense 3.0 as a best practice method in Europe’s largest market, Germany.
Skin Barrier Application
The second project is the result of three years of work cooperating with the SIAF institute in Davos, Switzerland. We have spoken for some time about our strategy to broaden the number of clinical applications for Nevisense and Electrical Impedance Spectroscopy (EIS).
Together with the team in Davos, we are developing a new application called ‘Skin Barrier function testing’. The first scientific article resulting from this cooperation is an animal study entitled ‘Direct assessment of skin epithelial barrier by electrical impedance spectroscopy’ which has just been published in the journal Allergy. The publication of this article, and an ongoing human trial mark SciBase’s entry into the barrier assessment space.
Skin barrier is an area with a very high level of clinical interest, and interest exists even at consumer level. The next time you are in a pharmacy, take a look at the number of moisturizers and skin cremes that mention ‘barrier’. The interest in barrier is growing exponentially and SciBase has found itself well positioned to take advantage of this interest.
So, what is the skin ‘barrier’? In the simplest sense, the skin’s barrier prevents external threats such as irritants, allergens and infectious agents from entering the body and prevents water from leaving the body. It achieves this through a complex combination of layers and mechanisms, but the most important of these from a barrier function perspective are two mechanical barriers – the outermost ‘stratum corneum’ layer and the epithelial cell layer with its ‘tight junctions’ in the underlying ‘stratum granulosum’ layer.
When these layers are defective or damaged, barrier related disorders often occur. The most common of these is atopic dermatitis (AD) or eczema. It has been shown that children with a defective or ‘leaky’ barrier are far more likely to develop eczema – so the barrier problem precedes the symptoms we know as eczema. Put simply, a poor barrier allows irritants to penetrate the skin and cause inflammation which we see as eczema rashes, itchiness and so on. We also know that children with a poor barrier function are more likely to develop food allergies, as the new understanding is that food allergies develop after sensitization that occurs through the skin. So a poor skin barrier is also a very important risk factor in the development of food allergies. Furthermore, diseases such as allergic rhinosinusitis and asthma also appear to be barrier-related and a subset of children who develop AD also go on to develop these diseases.
Clinicians call this progression of disorders the ‘atopic’ or ‘allergic march’ and recent studies show this to be very-much barrier-related. These disorders are very common and consume a lot of healthcare resources – for example atopic dermatitis affects 20% of children and 2-8% of adults. Understanding the integrity of the skin barrier is extremely important in the characterization and management of these disorders.
The challenge is that the method used to measure skin barrier function, called Trans Epidermal Water Loss (TEWL) is not a clinical method because it is time consuming and very sensitive to environmental and patient artifacts.
This is where EIS comes in. We know from work done fifteen years ago by Stig Ollmar that EIS is inversely correlated to TEWL – in other words that EIS can be used as a measure of barrier function. What the work in Davos has shown is that this correlation still holds, and our hope is that even more information is available from the measurement of EIS. Barrier diseases like AD are systemic diseases and so measurement on healthy skin can provide important information also.
SciBase has been fully occupied with new research co-operations within the area of skin barrier testing and we look forward to announcing new clinical studies at top research centers in the near future. We also see the potential to partner with one of the many industry players developing therapies in this space.
Looking to the near future, we believe that EIS can provide a quick and simple method for the measurement of the skin barrier. By leveraging our current platform and our machine learning tools, we hope to develop analyses that add real clinical value in this space of barrier-related disorders.
Looking to the mid-term future, we will continue to execute on our strategy and complete development of a simpler and easier next generation EIS device – and in doing so provide a platform for a screening device for EIS that can result in broad adoption both within and outside our current core customer group Dermatologists.
In the next CEO letter, we will update you on the further development of these areas and discuss the progress of Nevisense in the US.
For more information, please contact: Simon Grant, CEO SciBase Tel: +46 72 887 43 99 Email: [email protected]
SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and a FDA clearance in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on Nasdaq First North (“SCIB”). Further information is available at www.scibase.com.
The information was submitted for publication, through the agency of the contact person set out above, at 08.00 CET on April 25, 2019.
About SciBase and Nevisense
SciBase AB is a Swedish medical technology company, headquartered in Stockholm that has developed and sells a unique point-of-care device for evaluation of skin disorders such as skin cancer and atopic dermatitis. Its first product, Nevisense, helps doctors to detect malignant melanoma, the most dangerous type of skin cancer. SciBase was founded by Stig Ollmar, Associate Professor at The Karolinska Institute in Stockholm, Sweden. Nevisense is based on substantial research and has achieved excellent results in the largest clinical study ever conducted on the detection of malignant melanoma. Nevisense is CE marked in Europe, has TGA approval in Australia and a FDA clearance in the United States. Nevisense is based on a method called Electrical Impedance Spectroscopy (EIS), which uses the varying electrical properties of human tissue to categorize cellular structures and thereby detect malignancies and abnormalities. SciBase is listed on Nasdaq First North (“SCIB”). Further information is available at www.scibase.com.
